SeqBench

AvrII

CCTAGG5′ overhang (4)

AvrII is a 6 bp-recognition restriction enzyme. It runs best in rCutSmart at 37°C.

NEB buffer activity

Buffer% Activity
rNEBuffer 1.1100%
rNEBuffer 2.1100%
rNEBuffer 3.150%
rCutSmartbest100%
Incubation
37°C
Heat inactivation
80°C, 20 min
Star activity
None
Methylation blocked
None

CCTAGG.

Find AvrII sites in your own sequence

Paste a sequence below and this scans it for every AvrII recognition site — the same engine behind the full Restriction Sites tool, scoped to just this one enzyme.

Frequently asked questions

What does AvrII recognize?

AvrII recognizes the 6 bp sequence CCTAGG (5′→3′), cutting the top strand between position 1 and 2 within the site to leave a 5′ overhang of 4 bases.

What buffer should I use for AvrII?

rCutSmart gives the highest activity (incubate at 37°C).

Does AvrII have star activity?

No documented star activity under standard reaction conditions.

Is AvrII blocked by DNA methylation?

Not blocked by Dam, Dcm, or CpG methylation.

Can I heat-inactivate AvrII?

Yes — 80°C for 20 minutes.