Gene Explorer — Gene Model, Target Dossier & Expression Fingerprint
Search a gene and get its exon/CDS structure, a druggability/disease/drug/trial/paper dossier, and a GTEx + Human Protein Atlas expression fingerprint — all in one page.
🌐 Sends the gene symbol you enter to Ensembl, Open Targets, NCBI, UniProt, ChEMBL, ClinicalTrials.gov, Europe PMC, GTEx and the Human Protein Atlas — not processed on SeqBench's own server
Search a human gene symbol and get three sections, each rendering as soon as its own sources respond: a spliced-transcript gene model built from Ensembl's live exon/CDS map; a function and druggability dossier combining Open Targets (function, tractability, top associated diseases), an NCBI/UniProt plain-English summary, ChEMBL (known drugs and their clinical phase, cross-referenced with indications), ClinicalTrials.gov, and top-cited Europe PMC papers; and an expression fingerprint from GTEx (median TPM per tissue) and the Human Protein Atlas (subcellular localization, tissue specificity, protein class). No section blocks on a slower one, and every source that doesn't respond is listed rather than silently left blank.
A human gene symbol or Ensembl gene ID (e.g. "ENSG00000141510").
How to use the Gene Explorer tool
- 1Search a gene symbol ("TP53") or Ensembl gene ID, or load an example.
- 2Read the gene model diagram, then the dossier (function, tractability, top diseases, known drugs, trials, papers) as each source resolves.
- 3Check the expression fingerprint (GTEx tissue bars, HPA subcellular location/tissue specificity) and any "sources didn't respond" notice.
Frequently asked questions
Why do some sections say a source "didn't respond"?
Nine independent external sources power this page's three sections; each is called and rendered independently so one being slow or briefly down never blocks the others. When a source genuinely fails, it's listed explicitly ("sourceErrors") rather than the section being silently left blank — that way it's never ambiguous whether a source had no data versus wasn't reachable.
Where does each section's data come from?
Gene model: Ensembl's live exon/CDS map (the same one the HGVS Converter uses). Dossier: Open Targets (function, tractability, disease associations), NCBI/UniProt (a plain-English function summary), ChEMBL (known drugs, mechanism, clinical phase, indications), ClinicalTrials.gov (trials), and Europe PMC (top cited papers). Expression: GTEx v8 (median TPM per tissue) and the Human Protein Atlas (subcellular location, RNA tissue specificity, protein class).
How current is this data?
Each source is queried live on every search (short-TTL cached, not a stored snapshot), so it reflects that source's own current data — GTEx (v8) and ChEMBL/Open Targets/ClinicalTrials.gov/Europe PMC/HPA are each that provider's live public API, not a bundled or frozen dataset (unlike, for example, this site's Variant Annotator tool, whose ClinVar/gnomAD/CADD data is genuinely a frozen snapshot).
Is my input stored, and can I use this from code?
The gene symbol you enter is sent to the nine external sources listed above to build the page; nothing is stored by SeqBench. The three underlying tools (gene_model, gene_dossier, gene_expression) are each available via the REST API and the MCP server.
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